peritoneum

The Facts about Peritoneal Mesothelioma

Peritoneal mesothelioma is a rare form of mesothelioma that accounts for approximately 20% of all mesothelioma cases. Peritoneal mesothelioma affects the tissue lining the abdomen which is called the peritoneum hence the name of this form of the cancer. The peritoneum protects the contents of the abdomen and is therefore very important.

Currently, only one cause of peritoneal mesothelioma is known and this is exposure to asbestos dust and fibres. Only a couple of months of exposure to asbestos without sufficient protection can lead to peritoneal mesothelioma thirty to fifty years later. Those suffering from peritoneal mesothelioma are mostly elderly men who worked amongst asbestos decades ago when workers were not protected from asbestos dust. Many of these men are currently lodging multi-million dollar lawsuits against the companies who exposed them to asbestos. Asbestos fibres can get into the peritoneum in two different ways. The most common way they reach the peritoneum is by them getting trapped in the trachea (windpipe) and bronchi (inside the lungs) by mucus and end up being swallowed. From here they can pass through the intestine wall into the peritoneum. The second way in which asbestos fibres can reach the peritoneum is by them lodging inside the lungs. They then move into the lymphatic system and get transported to the peritoneum. Constant exposure to asbestos leads to a great number of fibres being built up in the peritoneum.

The symptoms of peritoneal mesothelioma are generally only felt when the cancer has developed greatly. The symptoms include nausea, vomiting, weight loss, abdominal pains and loss of appetite. As the cancer matures, the symptoms will become more pronounced and severe.

There are several treatments for peritoneal mesothelioma although all of them have a poor success rate. The likelihood of a patient surviving depends on how early and aggressively the cancer is treated. Chemotherapy, radiation therapy and surgery are the most commonly used methods of treatment. Research into the treatment of peritoneal mesothelioma is being conducted in research stations in the United States and by many pharmaceutical companies.

Peritoneal Mesothelioma The cancer of abdominal lining

One of the fatal types of mesothelioma is Peritoneal Mesothelioma in which the cancerous cells attack the lining of the abdomen called Peritoneum. Peritoneum is the thin membrane, which shields various organs of the abdomen and also provides a lubricating fluid to enable the organs to move and work properly. Peritoneal Mesothelioma, which affects this lining, is yet now a relatively rare disease that accounts for about 1/5 of all mesotheliomas. Its only known cause in the U.S. till date is previous exposure to asbestos.

Major symptoms

Though Mesothelioma is neither age nor sex specific, peritoneal Mesothelioma is mostly seen in men who are in the age group of 50-70 years. There are a number of symptoms of peritoneal mesothelioma most of which start appearing after 20, 30 or 50 years after the exposure to asbestos. These symptoms may include weight loss (however, waist line may increase), pain or swelling in the abdomen, weakness, loss of appetite, bowel obstruction, anemia, nausea and fever. Also, fluid often accumulates in the peritoneal space leading to a condition called Ascites.

Diagnosis of peritoneal mesothelioma

The initial step towards detection of peritoneal mesothelioma includes X-rays and CT scans. For confirmed diagnosis, however the doctor needs to do biopsy whereby a piece of tissue is cut from the affected part of the victims body and is placed under microscope for examination. If the disease is detected at an early stage it stands better chance of getting cured than the state of diffuse peritoneal mesothelioma, where the cancer has already spread to various parts.

The cure

Its true that peritoneal mesothelioma is fatal and leads to several deaths every year. However, with continued researches, several modes of treatments have been embarked upon and in the future there is a fair chance of the disease becoming absolutely curable. The types of treatment of peritoneal mesothelioma include surgery, radiation therapy and chemotherapy.

In surgery a part of the abdominal tissue is cut out to remove the tumor. At times the doctor may also need to remove a lung or a portion of the diaphragm as per the requirement of the surgery. Radiation therapy, the second method, requires the application of high energy X-rays to shrink the tumor and kill the malignant cells. The rays may be applied from an external machine or by placing the radiation source directly to the affected part of the body, by means of plastic tubes. Last treatment type is the chemotherapy whereby a combination of drugs is applied to kill the cancer cells. The drugs may be administered by mouth in the capsule form or may be applied intravenously via needle.

However, it is essential to mention that cost of treating any form of cancer is extravagant and you may consult a mesothelioma lawyer to earn you a handsome compensation from the authority who was responsible for your prior exposure to asbestos.

So learn more about peritoneal mesothelioma so that you can initiate the treatment at the very early stage and get cured.

Why Asbestos is Killing

We all heard of Absestos and the horrible consequences it has in our health. Asbestosis is “a form of lung disease (pneumoconiosis)” which causes interstitial fibrosis or scarring of the lungs.

Asbestosis is progressive and, for the most part, irreversible. Respiratory impairment worsens with time, even if exposure to asbestos has ceased. Asbestosis is usually found in asbestos workers and not in the general public. People with asbestosis have shortness of breath, often along with a cough. Asbestos cretes Mesothelioma, and Mesothelioma is a form of cancer which affects mesothelial tissue in the lungs, peritoneum or pericardium.

The biggest concern mesothelioma is that can arise both from visceral and parietal peritoneum. It is diagnosed in advanced stages in most cases, and it often takes considerable time to arrive at the correct diagnosis, as the mean symptoms-to-diagnosis time reported is 122 days. The most frequently reported initial symptoms are abdominal pain (35), anorexia, marked weight loss, and ascites ; less frequently night sweats and hypercoagulability. Clinical presentation with fever of unknown origin, intestinal obstruction, or surgical emergency (due to acute inflammatory lesions) have been reported. Mesothelioma (cancer of the mesothelium) is a disease in which cells of the mesothelium become abnormal and divide without control or order. They can invade and damage nearby tissues and organs. Mesothelioma treatment if mesothelioma attorneys texas.

Mesothelioma is defined as an ICD-O histology code of 9050-9053. Data are presented for a five-year time period. Mesothelioma cell viability was decreased in a dose-dependent manner by lovastatin (5 to 30 microM). These effects were not reversed by exogenous growth factors or cholesterol, but were reversed by addition of doses of micro mevalonate, confirming that lovastatin affected mesothelioma viability by inhibiting mevalonate synthesis. This is based on the fact that Mesothelioma is a cancer of the thin lining surrounding the lung and this disease is almost always fatal, often within a few months of diagnosis.

The scary part about this ilness, is that mesothelioma has a much longer latency period compared with lung cancer (40 years versus 15-20 years), and mesothelioma is therefore likely to be found among workers who were first exposed to asbestos at an early age. Mesothelioma is always fatal. Mesothelioma has also been found in individuals who were exposed to asbestos only once decades earlier. The only known cause of mesothelioma is asbestos. Mesothelioma has a much longer latency period compared with lung cancer (40 years versus 15-20 years), and mesothelioma is therefore more likely to be found among workers who were first exposed to asbestos at an early age. Mesothelioma is always fatal.

Exposure to asbestos has also been associated with an increased incidence of esophageal, kidney, laryngeal, pharyngeal, and buccal cavity cancers. As with other known chronic occupational diseases, disease associated with asbestos generally appears about twenty years following the first occurrence of exposure: There are no known acute effects associated with exposure to asbestos. Exposure to ozone for several hours at relatively low concentrations has been found to significantly reduce lung function and induce respiratory inflammation in normal, healthy people during exercise. This decrease in lung function generally is accompanied by symptoms including chest pain, coughing, sneezing, and pulmonary congestion. Exposure to environmental tobacco smoke (ETS) is a significant cause of lung cancers in people who themselves do not use tobacco. Between 3000 and 6000 lung cancer deaths per year in the United States are caused by exposure to ETS.

Symptoms of Mesothelioma – Know more; suffer less

What is Mesothelioma?

Mesothelioma can be defined as a rare form of cancer that affects mesothelium, the protective sac that covers most of the internal organs of the body. In this disease, the cells of the mesothelium become abnormal and they start dividing randomly. Mostly, the preliminary attack of Mesothelioma takes place in pleura or peritoneum and it is seen that majority of the Mesothelioma patients have a history of exposure to asbestos.

Mesothelioma’s nexus with asbestos

Mesothelioma is a relatively rare form of cancer with a rate of about 2000 new cases per year in the US. Though there is no specific age or sex for Mesothelioma, aged men seem to be more prone to catch the disease. As 70% to 80% of the case histories of patients reveal, Mesothelioma has a strong connection with asbestos exposure.

Asbestos is a group of minerals, which occur naturally as masses of strong, flexible fibers. It is required in several industries namely cement, flooring products, textiles, etc. When the tiny particles of asbestos are inhaled or swallowed, they pose severe health related threats like increased risk of lung cancer, asbestosis, mesothelioma, etc. The combination of asbestos exposure and smoking habit often aggravates the risk.

Symptoms of Mesothelioma

One peculiarity of Mesothelioma is that it has a long latency period of about 15-50 years, which means that the symptoms of the disease may start appearing 30 to 50 years after exposure to asbestos. Moreover, Mesothelioma symptoms are often not specific i.e. they are same in case of several other diseases. This is why Mesothelioma tests are very important to dispel the incidence of the disease if relevant symptoms crop up.

Speaking of symptoms, there are three prominent symptoms of Mesothelioma that cannot be overlooked. These involve pain while breathing or coughing, gasping for breath and a persistent cough that may result in sputum streaked with blood. Besides, exhaustion, weight loss and appetite loss are some of the other contributing symptoms. Other very rare symptoms are hoarse voice, swelling of the face or the neck, problem in swallowing and pain around the rib area.

However, depending upon the location of the cancerous tumors (pleura or peritoneum) the symptoms vary in case of pleural and peritoneal Mesothelioma. In pleural Mesothelioma, the fluid gets accumulated in the pleura and leads to shortness of breath, persistent coughing, pain in the chest, difficulty in sleeping, pain in the lower back and side of chest, husky voice, nausea, difficulty in swallowing and fever.

Cancer in the lining of the abdomen is what we know as peritoneal Mesothelioma. Because of the fluid retention in the abdominal cavity there is a subsequent abdominal pain and swelling.

Noticeable symptoms of peritoneal Mesothelioma are listed as follows:

– Weight loss
– Abdominal pain
– Build up of fluid in the abdomen
– Bowel obstruction
– Abnormal blood clotting
– Abdominal mass and fever

Mesothelioma’s treatment depends upon several factors like location of the cancer, stage of the disease, patient’s age and general health. Standard treatments that are carried out to cure the disease include surgery, radiation therapy, and chemotherapy. Sometimes, these treatments are combined to achieve better results.

Thus it is worthwhile to mention, as all doctors say that to fight a disease we need to find the symptoms first. So be aware of the symptoms of Mesothelioma and consult the doctor at the very onset for an immediate treatment.

Symptoms Of Asbestos Exposure!

We are all exposed to low levels of asbestos in the air we breathe. These levels range from 0.00001 to 0.0001 fibers per milliliter of air and generally are highest in cities and industrial areas.

It is known that breathing asbestos can increase the risk of cancer in people. There are two types of cancer caused by exposure to asbestos: lung cancer and mesothelioma. Mesothelioma is a cancer of the thin lining surrounding the lung (pleural membrane) or abdominal cavity (the peritoneum). Cancer from asbestos does not develop immediately, but shows up after a number of years. Studies of workers also suggest that breathing asbestos can increase chances of getting cancer in other parts of the body (stomach, intestines, esophagus, pancreas, and kidneys), but this is less certain. Early identification and treatment of any cancer can increase an individual’s quality of life and survival.

People working in industries that make or use asbestos products or who are involved in asbestos mining may be exposed to high levels of asbestos. People living near these industries may also be exposed to high levels of asbestos in air.

Asbestos fibers may be released into the air by the disturbance of asbestos-containing material during product use, demolition work, building or home maintenance, repair, and remodeling. In general, exposure may occur only when the asbestos-containing material is disturbed in some way to release particles and fibers into the air.

 

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